Thorne Zinc Picolinate 15mg – Highly Bioavailable Chelated Zinc | Supports Immune Health, Skin & Hormone Balance, 60 Capsules

What Is Thorne Zinc Picolinate 15mg?

Thorne Zinc Picolinate 15mg delivers 15 mg of zinc per capsule in the highly bioavailable zinc picolinate form — zinc chelated to picolinic acid, a natural organic acid produced by the body that facilitates active transport of zinc across intestinal epithelial cells. This chelated form is clinically shown to outperform zinc oxide and zinc sulfate in tissue retention and bioavailability. At 15 mg per capsule (136% DV), this is a daily maintenance dose ideally suited for long-term immune support, hormonal balance, and skin health without the risk of copper depletion associated with higher-dose zinc supplements. NSF Certified for Sport® and formulated with no unnecessary excipients — the Thorne standard trusted by healthcare practitioners globally.

What Does Zinc Picolinate Do?

• Immune System Defense — Zinc is the master mineral of immune function. It is required for the development, maturation, and activation of T-lymphocytes, natural killer (NK) cells, and neutrophils — the front-line defenders against pathogens. Zinc also has direct antiviral properties and is one of the most clinically validated nutrients for reducing the duration and severity of upper respiratory infections including the common cold
• Antioxidant Protection via Superoxide Dismutase (SOD) — Zinc is a structural cofactor of copper-zinc superoxide dismutase (Cu-Zn SOD), one of the body’s most critical antioxidant enzymes. SOD neutralizes superoxide radicals generated during cellular metabolism and immune activation, protecting tissues from oxidative damage
• Skin Health, Acne & Wound Healing — Zinc is essential for collagen synthesis, keratinocyte proliferation, and the regulation of sebaceous gland activity. It is one of the most well-studied natural interventions for acne vulgaris, reducing both inflammatory and non-inflammatory lesions by modulating sebum production, inhibiting P. acnes bacterial growth, and dampening skin inflammation. It also accelerates wound healing and tissue repair
• Testosterone & Reproductive Health — Zinc is a required cofactor for testosterone biosynthesis and the healthy function of the male reproductive system. It inhibits aromatase (the enzyme that converts testosterone to estrogen) and supports healthy sperm production, motility, and morphology. Zinc deficiency is directly correlated with reduced testosterone levels
• DNA Synthesis, Growth & Cell Division — Zinc is required for the catalytic activity of over 300 enzymes and over 2,000 transcription factors involved in DNA replication, gene expression, and cell division — fundamental to growth, tissue regeneration, and post-exercise recovery
• Thyroid & Metabolic Function — Zinc is required for the conversion of the inactive thyroid hormone T4 to the active T3 form, and for the synthesis of thyroid-releasing hormone (TRH). Adequate zinc supports healthy thyroid function and metabolic rate
• Brain Health & Neurotransmission — Zinc is highly concentrated in the hippocampus and plays roles in synaptic plasticity, NMDA receptor regulation, and the synthesis of BDNF (brain-derived neurotrophic factor), supporting memory, learning, and mood stability

Why 15mg? The Case for Maintenance Dosing

While higher-dose zinc supplements (25–50 mg) are sometimes used therapeutically, long-term use above 40 mg/day can deplete copper and cause adverse effects. Thorne’s 15 mg dose is specifically formulated for safe, effective daily maintenance — replenishing zinc stores depleted by stress, exercise, plant-based diets, and aging without the risk of copper antagonism. For individuals requiring higher therapeutic doses, a separate copper supplement can be co-administered under practitioner guidance.

Who Should Take This?

• Anyone seeking daily immune system maintenance and resilience
• Individuals with acne, eczema, or inflammatory skin conditions
• Men supporting healthy testosterone levels and reproductive function
• Vegans and vegetarians with lower zinc bioavailability from plant-based diets (due to phytate inhibition)
• Athletes with elevated zinc losses through sweat and high training loads
• Those supporting thyroid health and metabolic function
• Competitive athletes requiring NSF Certified for Sport® verified supplements

How to Use

Take 1 capsule daily with a meal, or as directed by your healthcare practitioner. Avoid taking on an empty stomach to minimize the possibility of nausea. For optimal absorption, space zinc supplementation at least 2 hours away from iron supplements, calcium supplements, or tetracycline/fluoroquinolone antibiotics.

Product Highlights

• 15 mg Zinc Picolinate per capsule — 136% DV, ideal daily maintenance dose
• Chelated form for maximum bioavailability and GI tolerability
• Supports Immune Defense, Skin Health, Testosterone & Thyroid Function
• SOD antioxidant cofactor — broad cellular protection
• 60 Capsules — 60-day supply at 1 capsule/day
• NSF Certified for Sport® | No unnecessary excipients
• From Thorne — trusted by healthcare practitioners worldwide