NOW Glycine 1000 mg – Nervous System Support, Promotes Restful Sleep, Pharmaceutical Grade, Free-Form, 100 Veg Capsules

What Is NOW Glycine 1000 mg?

NOW Glycine 1000 mg delivers a full gram of pharmaceutical-grade, free-form Glycine — the simplest amino acid and one of the most functionally diverse molecules in the human body. Glycine is classified as a conditionally essential amino acid: while the body can synthesize it, research increasingly suggests that endogenous production falls significantly short of the body’s total metabolic demand — particularly under conditions of stress, aging, collagen synthesis, glutathione production, and active detoxification. As both an inhibitory neurotransmitter in the spinal cord and brainstem and a critical substrate for dozens of biosynthetic pathways, glycine occupies a uniquely central role in human physiology. NOW’s pharmaceutical-grade, free-form glycine ensures maximum purity and bioavailability — no fillers, no binders, just pure glycine in a clean vegan capsule.

What Does Glycine Do?

• Nervous system support — Functions as an inhibitory neurotransmitter in the spinal cord and brainstem, regulating motor and sensory signal transmission and supporting neurological calm
• Promotes restful sleep — Clinical studies show glycine supplementation (3g before bed) lowers core body temperature, improves sleep onset, sleep quality, and daytime alertness without next-day grogginess; works through a different mechanism than melatonin
• Collagen synthesis — Glycine constitutes approximately 33% of all amino acids in collagen, making it the single most important amino acid for skin, joint, tendon, bone, and connective tissue health
• Glutathione production — One of three amino acids (with cysteine and glutamate) required to synthesize glutathione, the body’s master antioxidant
• Liver detoxification — Essential for Phase II hepatic conjugation — glycine conjugates bile acids and xenobiotics for safe biliary excretion
• Creatine synthesis — A direct precursor to creatine, the primary energy buffer in muscle and brain tissue
• Blood sugar metabolism — Low glycine is associated with insulin resistance; supplementation may support healthy glucose metabolism
• Anti-inflammatory effects — Glycine activates glycine-gated chloride channels on macrophages, suppressing pro-inflammatory cytokine release

Who Should Take This?

• Individuals seeking natural, non-habit-forming sleep support
• Those supporting skin, joint, and connective tissue health through collagen biosynthesis
• People supporting glutathione and liver detoxification pathways
• Athletes and active individuals supporting creatine synthesis and muscle recovery
• Older adults with increased glycine demand and declining endogenous synthesis
• Anyone supporting nervous system calm and healthy inflammatory balance

How to Use

Take 2 to 3 capsules daily with food, or as directed by your healthcare practitioner. For sleep support, take 3 capsules (3,000 mg) approximately 30 to 60 minutes before bedtime on an empty stomach or light snack. Glycine is well tolerated at doses up to 9g/day in research settings.

Product Highlights

• 1,000 mg Free-Form Glycine per capsule — Pharmaceutical Grade
• Nervous System Support — Restful Sleep — Collagen & Glutathione Precursor
• Non-habit forming natural sleep support — no grogginess
• Liver detox, creatine synthesis & anti-inflammatory support
• Vegetarian/Vegan capsules
• 100 Veg Capsules
• Non-GMO Verified
• No artificial colors, flavors, or preservatives
• Family Owned Since 1968