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Bio-Fisetin by Life Extension – Up to 25x Greater Bioavailability – 30 Vegetarian Capsules

Bio-Fisetin by Life Extension – Up to 25x Greater Bioavailability – 30 Vegetarian Capsules

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Life Extension Bio-Fisetin – Ultra-Bioavailable Fisetin for Senolytic, Longevity & Brain Health Support

Fisetin is a naturally occurring flavonoid found in strawberries, apples, and other fruits — and it has rapidly emerged as one of the most exciting longevity compounds in anti-aging science. Research suggests fisetin acts as a potent senolytic agent, helping to clear senescent (“zombie”) cells that accumulate with age and drive chronic inflammation and tissue dysfunction. Life Extension’s Bio-Fisetin uses a proprietary complexing technology to deliver fisetin with up to 25 times greater bioavailability than standard fisetin supplements — ensuring you get meaningful levels in circulation where the science shows it matters.

What Does Bio-Fisetin Do?

  • Acts as a senolytic to help clear senescent (“zombie”) cells that accumulate with aging
  • Supports healthy inflammatory balance and reduces senescence-associated secretory phenotype (SASP)
  • Promotes cognitive function, memory, and neuroprotection via multiple pathways
  • Activates sirtuins and supports NAD+ metabolism for cellular energy and longevity
  • Provides potent antioxidant protection at the cellular and mitochondrial level
  • Up to 25x greater bioavailability vs. standard fisetin through advanced complexing technology
  • Gluten-free, non-GMO vegetarian capsule formula

Who Should Take This?

Bio-Fisetin is ideal for adults focused on healthy aging, longevity, and cellular rejuvenation — particularly those interested in senolytic protocols. It is also well-suited for those seeking cognitive support, antioxidant protection, and healthy inflammatory balance as part of a comprehensive anti-aging supplement stack.

Product Highlights

  • Key Ingredient: Fisetin (as Novusetin™) – up to 25x enhanced bioavailability
  • Capsule Count: 30 Vegetarian Capsules
  • Brand: Life Extension
  • Technology: Advanced bioavailability-enhancing complex
  • Formula: Gluten-Free, Non-GMO

Frequently Asked Questions

What is a senolytic and why does it matter for aging?
Senescent cells are damaged cells that stop dividing but refuse to die — instead they linger and secrete inflammatory compounds (SASP) that damage surrounding healthy tissue. Accumulation of senescent cells is a key driver of aging, chronic disease, and tissue dysfunction. Senolytics like fisetin help selectively clear these cells, potentially slowing the aging process at a fundamental level.

Why does bioavailability matter for fisetin?
Standard fisetin has poor oral bioavailability due to its low water solubility and rapid metabolism. Bio-Fisetin’s Novusetin™ complex dramatically improves absorption, achieving blood levels up to 25x higher than conventional fisetin — which is critical for achieving the concentrations shown to be effective in research.

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Supplement Facts

Serving Size: 1 Capsule
Servings Per Container: 30

Amount Per Serving | % Daily Value
Fisetin (as Novusetin™)(from Rhus succedanea extract)(stem bark) | 100 mg | †

† Daily Value not established.

Other Ingredients: Microcrystalline cellulose, vegetable cellulose (capsule), silica, vegetable stearate.

Directions

Take one (1) capsule daily with or without food, or as recommended by a healthcare practitioner. Some longevity protocols use higher intermittent doses — consult your healthcare practitioner for personalized guidance.

Warnings

KEEP OUT OF REACH OF CHILDREN. Do not exceed recommended dose without physician supervision. Do not purchase if outer seal is broken or damaged. If you are taking medications metabolized by the liver (CYP enzymes), consult your physician before use as fisetin may interact with drug metabolism pathways. When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.