Thorne Magnesium Glycinate – Chelated for High Absorption | Supports Sleep, Muscle & Nerve Health, 90 Capsules

What Is Thorne Magnesium Glycinate?

Thorne Magnesium Glycinate is a premium magnesium supplement featuring magnesium chelated to glycine — one of the most bioavailable and well-tolerated forms of magnesium available. Unlike poorly absorbed forms such as magnesium oxide, magnesium glycinate is absorbed via a dedicated amino acid transport pathway in the intestinal wall, resulting in significantly higher tissue uptake with minimal laxative effect. Magnesium is involved in over 300 biochemical reactions in the body, making it one of the most essential and widely deficient minerals in modern diets. Thorne is an NSF Certified for Sport® brand trusted by professional athletes and healthcare practitioners worldwide.

What Does Magnesium Glycinate Do?

• Sleep Quality & Relaxation — Magnesium activates the parasympathetic nervous system (the "rest and digest" system) and regulates GABA receptors — the primary inhibitory neurotransmitter that promotes calm and sleep. Magnesium deficiency is strongly associated with insomnia, restless sleep, and nighttime muscle cramps. Glycinate, the amino acid chelate, has its own calming properties via glycine receptor activity in the brain, making magnesium glycinate the preferred form for sleep support
• Muscle Function & Recovery — Magnesium is essential for muscle contraction and relaxation. It acts as a natural calcium antagonist — while calcium triggers muscle contraction, magnesium is required to release it. Adequate magnesium prevents muscle cramps, spasms, and tightness, and supports faster recovery after exercise by reducing exercise-induced inflammation and oxidative stress
• Nervous System Support — Magnesium regulates nerve signal transmission by blocking NMDA receptors (which, when overstimulated, cause neurological excitotoxicity) and supporting healthy neurotransmitter balance. It plays a key role in stress resilience, anxiety reduction, and prevention of migraine headaches
• Energy Production & ATP Synthesis — ATP (the cell’s primary energy molecule) must be bound to magnesium to be biologically active. Every ATP-dependent enzymatic reaction in the body — including all cellular energy metabolism — requires magnesium as a cofactor. Magnesium deficiency directly impairs energy production at the cellular level
• Cardiovascular Health — Magnesium supports healthy blood pressure by relaxing the smooth muscle of blood vessels (vasodilation), regulating heart rhythm by controlling calcium flux in cardiac cells, and supporting healthy cholesterol and blood sugar metabolism
• Bone Health — Over 60% of the body’s magnesium is stored in bone. Magnesium works synergistically with calcium and Vitamin D to support bone mineral density and skeletal integrity
• Blood Sugar & Insulin Sensitivity — Magnesium is a required cofactor for insulin receptor signaling. Magnesium deficiency impairs insulin action, and supplementation has been shown to improve insulin sensitivity and support healthy blood glucose regulation

Why Magnesium Glycinate Over Other Forms?

• Highest Bioavailability — Chelation to glycine enables absorption via amino acid transporters, bypassing the saturable ion channels used by inorganic magnesium salts — resulting in superior tissue uptake
• Gentle on the GI Tract — Unlike magnesium oxide or magnesium citrate at high doses, magnesium glycinate does not cause diarrhea or digestive discomfort, making it suitable for daily, long-term use
• Dual Calming Effect — Both magnesium and glycine independently support relaxation and sleep quality, making glycinate the most targeted form for stress and sleep applications
• Thorne Quality Assurance — Thorne uses only chelated mineral forms (TRAACS® technology by Albion Minerals) to ensure consistent, verified bioavailability in every capsule

Who Should Take This?

• Individuals experiencing poor sleep quality, insomnia, or nighttime muscle cramps
• Those with chronic stress, anxiety, or nervous system hyperactivity
• Athletes and active individuals seeking muscle recovery and cramp prevention
• People with migraines or tension headaches associated with magnesium deficiency
• Individuals with cardiovascular concerns or blood sugar management goals
• Anyone with suboptimal magnesium intake — estimated 50–80% of the population is magnesium deficient

How to Use

Take 1–3 capsules daily, preferably in the evening with a meal or at bedtime, or as directed by your healthcare practitioner. For sleep support, take 1–2 capsules 30–60 minutes before bed. For muscle recovery, take after exercise. Start with a lower dose and increase gradually to assess individual tolerance.

Product Highlights

• Magnesium Glycinate — chelated form for maximum absorption & GI tolerance
• Supports Sleep, Relaxation, Muscle Recovery & Nerve Health
• Supports Energy Production, Cardiovascular Health & Blood Sugar Balance
• 90 Capsules — up to 45-day supply at 2 capsules/day
• From Thorne — NSF Certified for Sport®, trusted by healthcare practitioners
• No artificial additives, fillers, or unnecessary excipients