{"product_id":"thorne-magnesium-citramate-citrate-malate-energy-muscle-nerve-cardiovascular-90-capsules","title":"Thorne Magnesium CitraMate™ – Magnesium Citrate-Malate | Supports Energy, Muscle, Nerve \u0026 Cardiovascular Health, 90 Capsules","description":"\u003ch2\u003eWhat Is Thorne Magnesium CitraMate™?\u003c\/h2\u003e\u003cp\u003eThorne Magnesium CitraMate™ delivers magnesium as a unique \u003cstrong\u003ecitrate-malate complex\u003c\/strong\u003e — combining magnesium with both citric acid and malic acid, two key organic acids that are direct intermediates in the \u003cstrong\u003eKrebs cycle (citric acid cycle)\u003c\/strong\u003e, the mitochondrial pathway responsible for generating the majority of the body’s cellular energy (ATP). This dual-acid complex offers a distinct advantage over single-chelate magnesium forms: not only does it provide highly bioavailable magnesium, but the citrate and malate anions themselves contribute directly to mitochondrial energy metabolism, making Magnesium CitraMate™ the preferred magnesium form for individuals whose primary goals are \u003cstrong\u003eenergy production, fatigue reduction, and metabolic support\u003c\/strong\u003e — in addition to the full spectrum of magnesium’s systemic benefits. NSF Certified for Sport®.\u003c\/p\u003e\u003ch2\u003eWhat Makes Citrate-Malate Unique?\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCitrate (Citric Acid)\u003c\/strong\u003e — A central intermediate in the Krebs cycle; enters the mitochondria directly to support ATP synthesis, helps buffer lactic acid accumulation during exercise, and supports kidney stone prevention by increasing urinary citrate levels (a potent inhibitor of calcium oxalate crystal formation)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMalate (Malic Acid)\u003c\/strong\u003e — Another direct Krebs cycle intermediate; plays a critical role in the malate-aspartate shuttle, which transfers reducing equivalents into the mitochondria for ATP production. Malic acid supplementation has been specifically studied for fibromyalgia, chronic fatigue syndrome, and exercise-induced muscle pain, showing improvements in energy, pain reduction, and exercise tolerance\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCombined Effect\u003c\/strong\u003e — The citrate-malate complex simultaneously delivers bioavailable magnesium and two mitochondrial energy substrates in a single capsule, making this form uniquely suited for energy-focused applications compared to glycinate (sleep\/relaxation-focused) or oxide (laxative-effect, low bioavailability)\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eWhat Does Magnesium CitraMate™ Do?\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCellular Energy Production \u0026amp; Fatigue Reduction\u003c\/strong\u003e — Magnesium is required for every ATP-dependent enzymatic reaction in the body (ATP must be bound to magnesium to be biologically active), while citrate and malate directly feed into the Krebs cycle. This triple-action energy support makes CitraMate™ particularly effective for individuals with chronic fatigue, fibromyalgia, post-exercise fatigue, and energy metabolism impairment\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMuscle Function, Recovery \u0026amp; Cramp Prevention\u003c\/strong\u003e — Magnesium is the physiological antagonist of calcium in muscle cells — calcium triggers contraction, magnesium enables relaxation. Adequate magnesium prevents muscle cramps, spasms, and delayed-onset muscle soreness (DOMS). Malic acid’s role in lactic acid buffering further supports faster post-exercise recovery and reduced muscle pain\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNervous System Regulation \u0026amp; Stress Resilience\u003c\/strong\u003e — Magnesium regulates NMDA glutamate receptors (preventing excitotoxicity), supports GABA-ergic calming signaling, and modulates the HPA (hypothalamic-pituitary-adrenal) axis stress response. Deficiency is strongly associated with anxiety, hyperirritability, and poor stress tolerance\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCardiovascular Health\u003c\/strong\u003e — Magnesium supports healthy blood pressure through smooth muscle relaxation and vasodilation, regulates cardiac rhythm by modulating calcium flux in cardiac cells, and supports healthy cholesterol and blood glucose metabolism. Epidemiological data consistently links higher magnesium intake with lower cardiovascular disease risk\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eKidney Stone Prevention\u003c\/strong\u003e — Magnesium and citrate work synergistically to reduce urinary calcium oxalate supersaturation — the primary driver of the most common form of kidney stones. Citrate inhibits calcium oxalate crystal growth and aggregation in the urinary tract, and magnesium reduces intestinal oxalate absorption\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBlood Sugar \u0026amp; Insulin Sensitivity\u003c\/strong\u003e — Magnesium is a required cofactor for insulin receptor tyrosine kinase activity. Deficiency impairs insulin signaling, and supplementation supports improved insulin sensitivity and healthy postprandial blood glucose regulation\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBone Health\u003c\/strong\u003e — Over 60% of the body’s magnesium is stored in bone as a structural component of the bone mineral matrix. Adequate magnesium is essential for hydroxyapatite crystal formation, bone mineral density, and the proper function of osteoblasts (bone-building cells)\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eMagnesium CitraMate™ vs. Other Magnesium Forms\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003evs. Magnesium Glycinate\u003c\/strong\u003e — Glycinate is the preferred form for sleep and relaxation (glycine has direct calming receptor activity). CitraMate™ is the preferred form for energy production, fatigue, and metabolic support due to the Krebs cycle contribution of citrate and malate\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003evs. Magnesium Citrate\u003c\/strong\u003e — Standard citrate provides citric acid but not malic acid. CitraMate™’s addition of malate adds a second Krebs cycle intermediate, broadening mitochondrial energy support and adding malic acid’s specific benefits for fibromyalgia and muscle pain\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003evs. Magnesium Oxide\u003c\/strong\u003e — Oxide has very low bioavailability (~4%) and primarily acts as a laxative. CitraMate™ is substantially more bioavailable and does not cause diarrhea at standard doses\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003evs. Magnesium Malate\u003c\/strong\u003e — Pure malate provides malic acid but not citrate. CitraMate™’s inclusion of both citrate and malate provides broader Krebs cycle coverage and the additional kidney stone prevention benefit of citrate\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eWho Should Take This?\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eIndividuals with chronic fatigue, low energy, or fibromyalgia seeking mitochondrial energy support\u003c\/li\u003e\n\u003cli\u003eAthletes seeking faster muscle recovery, cramp prevention, and reduced exercise-induced fatigue\u003c\/li\u003e\n\u003cli\u003eThose supporting cardiovascular health through blood pressure and cardiac rhythm regulation\u003c\/li\u003e\n\u003cli\u003eIndividuals with a history of kidney stones (calcium oxalate type) seeking magnesium + citrate prevention support\u003c\/li\u003e\n\u003cli\u003ePeople with metabolic concerns including blood sugar regulation and insulin sensitivity\u003c\/li\u003e\n\u003cli\u003eAnyone with suboptimal magnesium intake who primarily needs energy and metabolic support (vs. sleep support)\u003c\/li\u003e\n\u003cli\u003eCompetitive athletes requiring NSF Certified for Sport® verified supplements\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eHow to Use\u003c\/h2\u003e\u003cp\u003eTake 1–3 capsules daily with a meal, or as directed by your healthcare practitioner. For energy and metabolic support, morning or midday dosing with food is recommended. For muscle recovery, take after exercise. Start with 1 capsule daily and increase gradually to assess individual tolerance. For sleep support, consider Thorne Magnesium Glycinate instead, which pairs glycine’s calming effects with magnesium’s relaxation benefits.\u003c\/p\u003e\u003ch2\u003eProduct Highlights\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eMagnesium Citrate-Malate — dual Krebs cycle intermediate for enhanced energy support\u003c\/li\u003e\n\u003cli\u003eSupports Cellular Energy (ATP), Muscle Recovery \u0026amp; Fatigue Reduction\u003c\/li\u003e\n\u003cli\u003eMalic Acid — specifically studied for fibromyalgia and chronic fatigue\u003c\/li\u003e\n\u003cli\u003eCitrate — supports kidney stone prevention and lactic acid buffering\u003c\/li\u003e\n\u003cli\u003eSupports Cardiovascular Health, Blood Sugar \u0026amp; Bone Density\u003c\/li\u003e\n\u003cli\u003e90 Capsules | NSF Certified for Sport® | No unnecessary excipients\u003c\/li\u003e\n\u003cli\u003eFrom Thorne — trusted by healthcare practitioners worldwide\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Thorne","offers":[{"title":"90","offer_id":52899197419802,"sku":"THR-MAGCIT-90CAP","price":30.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1006\/7007\/9258\/files\/magnesium_citramate_thorne.jpg?v=1789625869","url":"https:\/\/bpbalance.com\/products\/thorne-magnesium-citramate-citrate-malate-energy-muscle-nerve-cardiovascular-90-capsules","provider":"BPBalance","version":"1.0","type":"link"}